Graves' Disease Associated with Cerebrovascular Disease and Antiphospholipid Antibody Syndrome

A Case of Gaucher\'s Disease with Recurrent Fetal Loss and Antiphospholipid Antibody Syndrome

Propylthiouracil-induced lupus, antiphospholipid syndrome, and stroke in a patient with Graves hyperthyroidism.

OBJECTIVE To describe a case of propylthiouracil-induced lupus, complicated with antiphospholipid syndrome and acute ischemic stroke. DESIGN Case report. SETTING Academic medical center. PATIENT A 27-year-old man with a diagnosis of Graves disease developed multiple ischemic strokes 2 weeks after starting treatment with propylthiouracil. Thyrotoxicosis and abnormal hypercoagulable and rhe...

Antiphospholipid Antibody Syndrome Associated with Graves’ Disease Presenting As Inferior Vena Cava Thrombosis with Bilateral Lower Limb DVT

We report a case of a 60-year-old lady who presented with bilateral lower limb swelling and a thyroid swelling with clinical features consistent with thyrotoxicosis. Investigations revealed the presence of a thrombus in bilateral external, internal iliac veins, and inferior vena cava extending up to its infrahepatic part. Hormone profile and radioiodine uptake scan confirmed the diagnosis of Gr...

Rare association of schizophrenia and unilateral Graves’ disease with contralateral thyroid hemiagenesis in two cases of McCune-Albright syndrome

The classical triad of McCune-Albright syndrome (MAS) consists of polyostotic fibrous dysplasia (FD), skin hyperpigmentation (café-au-lait spots), and endocrine dysfunction, frequently seen in females as precocious puberty. Etiology is genetically based and is explained by mosaicism of activating somatic mutations of the alpha-subunit of Gs protein. Clinical presentation is varied and is depend...

ANTIPHOSPHOLIPID ANTIBODY SYNDROME-A CASE OF AORTIC VALVE INSUFFICIENCY

A 31 year old woman was hospitalized for evaluation of aortic valve insufficiency and her present cardiac status. Clinical and paraclinical findings strongly suggested the presence of a collagen vascular inflammatory processprecisely, the antiphospholipid antibody syndrome (APS), with systemic lupus erythematosus as the underlying disease.